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Tse-Ling Fong, M.D., FACP
Curriculum Vitae
Personal Information
Name
Tse-Ling Fong, M.D., FACP
Business Address
USC Liver Transplant Program and Center for Liver Disease
1510 San Pablo Street
Suite 200
Los Angeles CA 90033-4612
Phone: (323) 442-5908
Fax: (323) 442-5721
Medical Licensure and Certification
- National Board of Medical Examiners, June 1983
- Board Certification
- American Board of Internal Medicine, September 1985
- Sub-specialty; Gastroenterology, November 1989
Education
-
1968-1974
Secondary School
King George V School
Hong Kong
- 1974-1978
B.A., (cum laude)
University of California, San Diego
- 1978-1982
M.D., University of Southern California
School of Medicine
Postdoctoral Training
1982-1985
Residency, Internal Medicine
LAC/USC Medical Center
Los Angeles, California
1985-1987
Fellowship, Hepatology
USC Liver Unit
Rancho Los Amigos Medical Center
Downey, California
1987-1989
Fellowship, Gastroenterology
LAC/USC Medical Center
Los Angeles, California
1989-1991
Clinical Associate
Liver Diseases Section, NIDDK
National Institutes of Health
Bethesda, Maryland
Academic Appointments
- 1985-1989
Clinical Instructor in Medicine
University of Southern California
School of Medicine
Los Angeles, California
- 1991-1996
Assistant Professor of Medicine
University of Southern California
School of Medicine
Los Angeles, California
- 1996-2001
Assistant Professor of Medicine
University of California, Los Angeles
School of Medicine
Los Angeles, California
- 2001
Associate Professor of Medicine
University of Southern California
Keck School of Medicine
Los Angeles, California
Hospital Appointments
- 1991- 1996
Attending Physician
LAC/USC Medical Center
Los Angeles, California
1991- 1996
Attending Physician
Rancho Los Amigos Medical Center
Downey, California
1996- 2001
Associate Medical Director
Liver Transplantation Program
Cedars-Sinai Medical Center
Los Angeles, California
2001
Medical Director
Liver Transplant Program
USC Keck School of Medicine
Los Angeles, California
Honors and Awards
- Provost Honor List 1974-1976, University of California, San Diego
- President's Fellowship for Undergraduate Research, 1977-1978, University of California,
San Diego
- National Institute of Mental Health Research Fellowship, 1979-1980, University of Southern California, School of Medicine
- University of Southern California, School of Medicine Research Fellowship 1980-1981
- Sigma-Xi Research Honor Society Research Grant, 1980-1981, University of Southern California, School of Medicine
- Golden Apple Teaching Award 1996-1997, Department of Medicine, Cedars-Sinai Medical Center
Reviewer
- Hepatology 1990-
- Gastroenterology 1991-
- American Journal of Gastroenterology 1994-
- Annals of Internal Medicine 1997-
- Clinical Infectious Disease 1998-
Society Memberships
- American College of Physicians, Fellow
- American Association for the Study of Liver Diseases
- American Society of Transplant Physicians
- Western Society for Clinical Investigation
- Southern California Society for Gastroenterology
Committees
Cedars-Sinai Medical Center
- Clinical Competency Committee 1997-
- Institutional Review Board 1998-
Southern California Gastroenterology Society
Publications-Peer Reviewed
- White K, Shih J, Fong T-L, Young H, Gelfand R, Boyd J, Simpson G, Sloane B.
Elevated Platelet Monoamine Oxidase Activity in Patients with Nonendogenous
Depression. American Journal of Psychiatry 1980;137:1258-1260.
- Radin R, Fong T-L , Halls J, Pontrelli G. Monilial Enteritis in Acquired Immunodeficiency Syndrome. AJR 1983;141:1289-1290.
- Fong T-L, De Cock KM, Govindarajan S, Yamada S, Morgan TR, Redeker AG.
Clustering of Delta Hepatitis in a Family from Lebanon, Journal of Infectious
Diseases 1986;154:912-913.
- Govindarajan S, Fong T-L, Ashcavai M. Concanavalin A Affinity of Alpha-Fetoprotein - Its Use in Differentiating Tumors. American Journal of Clinical Pathology 1987;88:722-724.
- Govindarajan S, Fong T-L, Valinluck B, Edwards V, Redeker AG. Markers of Viral Replication in Patients with Chronic Hepatitis B Virus Infection. American Journal of Clinical Pathology 1988;89:233-237.
- Fong T-L, Govindarajan S, Valinluck B, Redeker AG. Status of HBV-DNA in
Alcoholic Liver Disease: A Study of a Large Urban Population in the United States.
Hepatology 1988;8:1602-1604.
- Fong T-L, Warner N, Kumar D. Pancreatic Nesidioblastosis in Adults. Diabetes Care
1989;12:108-114.
- Fong T-L, Akriviadis E, Runyon BA, Reynolds TB. Polymorphonuclear Cell Count
Response and Duration of Antibiotic Therapy in Spontaneous Bacterial Peritonitis. Hepatology 1989;9:423-426.
- Fong T-L, Akriviadis E, Govindarajan S, Valinluck B, Redeker AG. Serum Hepatitis B Viral DNA in Acute Viral Hepatitis B. Annals of Internal Medicine 1989;110:937-38.
- Akriviadis E, Steindel H, Pinto P, Fong T-L, Kanel G, Reynolds TB, Gupta S. Failure of
Colchicine to Improve Short-Term Survival in Patients with Severe Alcoholic Hepatitis. Gastroenterology 1990;99:811-818.
- Gupta S, Govindarajan S, Fong T-L, Redeker AG. Spontaneous Reactivation in Chronic Hepatitis B: Patterns and Natural History. Journal of Clinical Gastroenerology 1990;12:562-568.
- Fong T-L, Dooley CP, Dehesa M, Cohen H, Carmel R, Fitzgibbons P, Perez-Perez GI, Blaser MJ. Helicobacter Pylori Infection in Pernicious Anemia: A Prospective Controlled Study. Gastroenterology 1991;100:328-332.
- Fong T-L, Di Bisceglie AM, Waggoner JG, Banks SM, Hoofnagle JH. The Significance of Antibody to Hepatitis C Virus in Patients with Chronic Hepatitis B. Hepatology 1991;14:64-67.
- Fong T-L, Shindo M, Feinstone SM, Hoofnagle JH, Di Bisceglie AM. Detection of Replicative Intermediates of Hepatitis C Viral RNA in Liver and Serum of Patients
with Chronic Hepatitis C. Journal of Clinical Investigation 1991;88:1058-1060.
- Fried MW, Shindo M, Fong T-L, Fox P, Hoofnagle JH, Di Bisceglie AM. Absence
of HCV RNA from Saliva and Semen in Patients with Chronic Hepatitis C.
Gastroenterology 1992;102:1306-1308.
- Fong T-L, McHutchison JG, Reynolds TB. Hyperthyroidism and Hepatic Dysfunction: A Case Series Analysis. Journal of Clinical Gastroenterology 1992;14:240-244.
- De Bisceglie AM, Shindo M, Fong T-L, Fried MW, Swain MG, Bergasa NV, Axiotis CA, Waggoner JG, Park Y, Hoofnagle JH. A Pilot Study of Ribavirin Therapy for Chronic Hepatitis C. Hepatology 1992;16:649-654.
- Fong T-L, Charboneau F, Valinluck B, Govindarajan S. The Stability of Serum HCV RNA in Various Handling and Storage Conditions. Archives of Pathology and Laboratory Medicine 1993;117:150-151.
- Fong T-L, Valinluck B, Govindarajan S, Rolon N, Lee SR, Page E, Darner J, Redeker AG. Marked Improvement in Sensitivity of Second Generation Tests for Acute Hepatitis C Infection. Journal of Infectious Diseases 1993;168:519-520.
- Fong T-L, Di Bisceglie AM, Gerber MA, Waggoner JG, Hoofnagle JH. Persistence
of HBV DNA in the Liver after Loss of Hepatitis B Surface Antigen from Serum of
Patients with Chronic Hepatitis B. Hepatology 1993;18:1313-1318.
- Di Bisceglie AM, Fong T-L, Fried MW, Swain MG, Baker B, Korenman J, Bergasa NV, Waggoner JG, Park Y, Hoofnagle JH. A Randomized, Controlled Trial of Recombinant Alpha-Interferon Therapy for Chronic Hepatitis B. American Journal of Gastroenterology 1993;88:1887-1892.
- Person JL, McHutchison JG, Fong T-L, Redeker AG. A Case of Cyclosporin-Sensitive, Steroid Resistant Autoimmune Chronic Active Hepatitis. Journal of Clinical Gastroenterology 1993;17:317-320.
- Fong T-L, Kanel GC, Conrad A, Valinluck B, Charboneau F, Adkins RH. The Clinical Significance of Concomitant Hepatitis C Infection in Patients With Alcoholic Liver Disease. Hepatology 1994;19:554-557.
- Fong T-L, Di Bisceglie AM, Biswas R, Waggoner JG, Wilson L, Claggett J, Hoofnagle JH. High Levels of Viral Replication During Acute Hepatitis B Infection Predict Progression to Chronicity. Journal of Medical Virology 1994;43:155-158.
- Fried MW, Fong T-L, Swain MG, Park Y, Beames M, Banks SM, Hoofnagle JH, Di Bisceglie AM. Therapy of Chronic Hepatitis B With A 6-Month Course of Ribavirin. Journal of Hepatology 1994;21:145-150.
- Fong T-L, Valinluck B, Govindarajan S, Charboneau F, Adkins RH, Redeker AG. Effects of Prednisone Therapy on Aminotransferase Activity and Hepatitis C Virus RNA Levels in Chronic Hepatitis C. Gastroenterology 1994;107:196-199.
- Shindo M, Di Bisceglie AM, Akatsuka T, Fong T-L, Scaglione L, Donets M, Hoofnagle JH, Feinstone S. The Physical State of the Negative Strand of HCV RNA in Serum of Patients with Chronic Hepatitis C Proceedings of the National Academy of Science USA 1994;91:8719-8723.
- Fong T-L, Morgan TR, Phan CG, Hoefs JC. Raising the Dose of Interferon Does Not Improve the Response in Chronic Hepatitis C. Journal of Clinical Gastroenterology 1995;20:42-44.
- Mican JM, Di Bisceglie AM, Fong T-L, Travis WD, Kleiner DE, Baker B, Metcalfe DD. Hepatic Involvement in Mastocytosis: Clinicopathologic Correlations in 41 Cases. Hepatology 1995;22:1163-1170.
- Fong T-L, Lee SR, Briggs WK, Valinluck B, Govindarajan, S, Hoffman A, Jaczko B, Redeker AG. Clinical Significance of Hepatitis C Viral RNA Status and its Correlation to Antibodies to Structural HCV Antigens in Anti HCV Reactive Patients With Normal Liver Tests. Journal of Medical Virology 1996;49:253-258.
- Fong T-L, Lee SR, Kim J, Yun AJ, Zheng J, Peterson J, Kochesky R Botla R, Geller SA, Redeker AG. Prevalence of Hepatitis G Virus Among Intravenous Drug Users In Los Angeles. Clinical Infectious Diseases 1997; 25:487-488.
- Tsai NCS, Zuckerman E, Han S-H, Goad K, Redeker AG, Fong T-L. The Effect of Iron
Depletion on Long-Term Response to a-Interferon in Patients with Chronic Hepatitis C Who Previously Did Not Respond to Interferon Therapy. American Journal of Gastroenterology 1997;92:1831-1834.
- Zuckerman E, Zuckerman T, Levine AM, Douer D, Gutekunst K, Mizokami M, Qian DG, Velankar M, Nathwani BN, Fong T-L. Hepatitis C Virus Infection in Patients with B-Cell Non-Hodgkin's Lymphoma. Annals of Internal Medicine 1997;127:423-428.
- Fong T-L, Han S-H, Tsai NC-S, Morgan TR, Mizokami M, Qian D, Phan C, Goad K, Redeker AG. A Pilot Randomized, Controlled Trial of the Effect of Iron Depletion on Long-Term Response to Alfa-Interferon in Patients with Chronic Hepatitis C. Journal of Hepatology 1998;28:369-374 .
- Fernandes NF, Geller SA, Fong T-L. Terbinafine Hepatotoxicity: Case Report and Review of the Literature. American Journal of Gastroenterology 1998; 93: 459-460.
- Han S-H, Reynolds TB, Fong T-L. Nephrogenic Ascites: Analysis of 16 Cases and Review of the Literature. Medicine 1998; 77:233-45.
- Fernandes NF, Redeker AG, Vierling JM, Villamil F, Fong T-L. Cyclosporin Therapy in Patients with Steroid Resistant Autoimmune Hepatitis: A Case Series and Review of the Literature. American Journal of Gastroenterology 1999; 94: 241-8.
- Fong T-L, Fried MW, Clarke-Platt J. A Pilot Study of Rimantadine for Patients with Chronic Hepatitis C Unresponsive to Interferon Therapy. American Journal of Gastroenterology 1999; 94: 990-93.
- Kahn JA, Haker KM, Petrovic LM, Arnaout WA, Koobatian G, Fong T-L. Radiographic Findings of Ischemic Hepatitis in a Cirrhotic Patient. Journal of Computer Assisted Tomography 2000;24-887-889.
- Yu AS, Vierling JM, Colquhoun SD, Arnaout AS, Chan C-K, Khansfshar E, Geller SA, Nichols WS, Fong T-L. Transmission of Hepatitis B Infection from Hepatitis B Core Antibody Positive Liver Allografts is Prevented by Lamivudine Therapy. Liver Transplantation 2001 (in press)
- Pruthi J, Medkiff KA, Esrason KT, Donovan JA, Yoshida EM, Erb SR, Steinbrecher UP, Fong T-L. Analysis of Causes of Death in Liver Transplant Recipients who Have Survived More Than Three Years. Liver Transplantation 2001 (in press)
- Fong T-L, Bunnapradist S, Jordan SC, Cho YC. Impact of Hepatitis B core Antibody Status on Outcomes of Cadaveric Renal Transplantation: Analysis of UNOS Database Between 1994 and 1999. Transplantation 2001 (in press)
Abstracts
- Fong T-L, Reynolds TB. Polymorphonuclear (PMN) Cell Count Response and Duration of Antibiotic Therapy in Spontaneous Bacterial Peritonitis (SBP). Hepatology 1986;6:1216.
- Fong T-L, Govindarajan S, Valinluck B, De Cock KM, Redeker AG. Hepatitis B Virus DNA in Alcoholic Disease. Hepatology 1986;6:1216.
- Fong T-L, Akriviadis E, Govindarajan S, Valinluck B, Redeker AG. Serum HBV-DNA in Acute Hepatitis B Infection. Hepatology 1987;7:1121.
- Akriviadis E, Steindel H, Pinto P, Fong T-L, Kanel G, Reynolds TB, Gupta S. Failure of Colchicine to Improve Short-Term Survival in Patients with Severe Alcoholic Hepatitis. Hepatology 1988;8:1239.
- Fong T-L, Dehesa M, Dooley CP, Cohen H, Fitzgibbons P, Carmel R, Perez-Perez GI, Blaser MJ. The Prevalence of Campylobacter Pylori in Patients with Pernicious Anemia. Gastroenterology 1989;96:A154.
- Fong T-L, Dooley CP, Dehesa M, Cohen H, Fitzgibbons P, Carmel R, Perez-Perez GI, Blaser MJ. Gastritis Types A and B are Distinct Entities. American Journal of Gastroenterology 1989;84:1157.
- Fong T-L, Di Bisceglie AM, Waggoner JG, Hoofnagle JH. The Significance of Concomitant Chronic Hepatitis B and Hepatitis C Virus Infection. The 1990 International Symposium on Viral Hepatitis and Liver Disease.
- Fong T-L, Di Bisceglie AM, Waggoner JG, Biswas R, Hoofnagle JH. High Levels of Serum HBV-DNA and HBsAg in Acute Hepatitis B Virus Infection Predict Progression to Chronicity. Hepatology 1990;12:845.
- Hoofnagle JH, Di Bisceglie AM, Baker B, Korenman J, Bergasa N, Fong T-L, Waggoner JG, Park Y. Treatment of Patients with Decompensated Cirrhosis Due to Chronic Hepatitis B with Recombinant Human Alpha Interferon. Hepatology 1990;12:846.
- Di Bisceglie AM, Fong T-L, Fried MW, Swain M, Bergasa N, Shindo M, Hoofnagle JH. Ribavirin Therapy for Six Months in Patients with Chronic Hepatitis C. Gastroenterology 1991;100:A735.
- Fong T-L, Di Bisceglie AM, Feinstone SM, Waggoner JG, Axiotis CA, Hoofnagle JH. Persistent Hepatic HBV-DNA After Clearance of HBsAg From Serum of Patients with Chronic Hepatitis. Hepatology 1991;130A;332.
- Di Bisceglie AM, Bergasa NV, Fong T-L, Fried MW, Swain M, Baker B, Korenman J, Waggoner JG, Park Y, Hoofnagle JH. A Randomized Controlled Trial of Recombinant Alpha Interferon Therapy for Chronic Hepatitis B. Hepatology 1992:70A.
- Fried MW, Swain MG, Fong T-L, Hayorka R, Ruddel M, Barnett JA, Hoofnagle JH, Di Bisceglie AM, Jones EA. The Monoethylglycinexylidide (MEGX) Test of Hepatic Function in Chronic Viral Hepatitis. Hepatology 1991;14;895.
- Shindo M, Mullin EG, Di Bisceglie AM, Fong T-L, Braun-Elwert L, Hoofnagle JH Jones EA, James SP. Cytokine mRNA Expression in the Liver of Patients with Chronic Hepatitis B. Gastroenterology 1991;100:A796.
- Fried MW, Fong T-L, Swain MG, Park Y, Simpson LH, Hoofnagle JH, Di Bisceglie AM. Hepatitis B Virus (HBV) DNA Suppression During Long-Term Therapy with Ribavirin. Gastroenterology 1992;102:A808.
- Shindo M, Fong T-L, Di Bisceglie AM, Hoofnagle JH, Feinstone SM. The Physical State of the Negative Strand of HCV RNA in Serum of Infected Patients. Gastroenterology 992;102:A887.
- Saxena S, Korula J, Fong T-L, Shulman IA. Prevalence of Hepatitis C Virus Infection and its Correlation with ALT Level Among Blood Donors at a Large Teaching Hospital. Hepatology 1992;16:220A.
- Bergasa NV, Alling DW, Talbot TL, Swain MG, Fried MW, Fong T-L, Yurdaydin C, Schmitt JM, Walker EC, Turner ML, Jones EA. Naloxone Ameliorates the Pruritus of Cholestasis: Results of a Double-Blind Randomized Placebo-Controlled Trial. Hepatology 1992;16:152A.
- Fong T-L, Valinluck B, Govindarajan S, Charboneau F, Adkins RH, Redeker AG. Effect of Short-Term Prednisone Administration on Aminotransferase (ALT) Levels and HCV-RNA In Patients With Chronic Hepatitis C. Hepatology 1993;18:87A.
- Morgan K, Peng X, Fong T-L, Kanel G, Chang C, Morgan TR. Preparation of a cDNA Library From Human Alcoholic Hepatitis Liver. Hepatology 1993;18:272A.
- Fong T-L, Briggs WK, Valinluck B, Govindarajan S, Redeker AG. Do Patients With Normal ALT and Anti-HCV Reactivity Have Occult Infection? Hepatology 1994;20:348A.
- Lee SR, Page E, Francis B, Fong T-L, Redeker A, Darner J, Gust C, Quan S, DiNello B, Polito A, Nelles M, Achord D. Improved Detection of Anti-HCV In Patients With Liver Disease By 3RD Generation HCV Assays. Hepatology 1994;20:240A.
- Han S-H, Fong T-L, Valinluck B, Adkins RH, Redeker AG. Randomized Controlled Trial of the Effect of Iron Depletion on Aminotransferase Levels, HCV RNA and Response to Interferon Therapy in Patients With Chronic Hepatitis C Virus. Hepatology 1995;22:180A.
- Han S-H, Rice S, Pedersen H, Stewart C, Reynolds TB, Fong T-L. Ultrasonogram
Determination of the Hepatic Artery Resistive Index Can Accurately Diagnose Acute Alcoholic Hepatitis. Hepatology 1996;24:146A.
- Pham T-V, Nanji AA, Fong T-L, Lin M, Yin W, Wang SC, Ohata M, Tsukamoto H. Iron and Unsaturated Fat As Nutritional Prooxidants: NF-B Activation, Induction of TNF and MIP-1 in Experimental ALD. Hepatology 1996;24:185A.
- Zuckerman E, Zuckerman T, Levine AM, Douer D, Gutekunst K, Fong T-L. Prevalence Of Hepatitis C Virus Infection In Patients With B-Cell Non-Hodgkin's Lymphoma. Hepatology 1996;24:377A.
- Zuckerman E, Zuckerman T, Levine AM, Douer D, Gutekunst K, Fong T-L. Is Hepatitis C Infection Associated With Severe Hepatitis In Patients With Hematological Malignancies Treated With Chemotherapy? Hepatology 1996;24:379A.
- Han SH, Tsai N, Morgan TR, Adkins R, Redeker AG, Fong T-L. A Pilot Randomized, Controlled Trial Of The Effect Of Iron Depletion On Long-Term Response To (-Interferon In Patients With Chronic Hepatitis C Virus. Hepatology 1996;24:405A.
- Peterson JE, Zheng J, Fong T-L, Kim JP, Kochesky R, Botla R, Redeker AG, Yun A, Geller SA, Nelles M, Lee SR. Prevalence and Persistence of Hepatitis G Virus High Risk Populations. Hepatology 1996;24:417A.
- Zuckerman E, Tsai N, Han S-H, Redeker AG, Fong T-L. Failure of Iron Depletion to Improve Response In Chronic Hepatitis C Patients Who Were Non-Responders to Prior Interferon Treatment. Hepatology 1996;24:604A.
- Akriviadas EA, Cohen SM, Chen DCP, Valinluck B, Stewart CA, Fong T-L.. Thrombopoietin (TPO) Levels Are Increased In Patients With Cirrhosis And Do Not Appear To Play A Role In The Pathogensis Of Thrombocytopenia Of Cirrhosis. Hepatology 1997;26:184A.
- Peterson JE, Kochesky R, Zheng J, Chien D, Fong T-L, Kim JP., Redeker AG, Geller SA., Nelles M, Lee SR. Prevalence of Antibody to Hepatitis G Virus in High Risk Populations. Hepatology 1997;26:324A.
- Arnaout WS, Colquhoun SD, Petrovic LM, Fong T-L, Goldman DE, Vierling JM, Shackleton CR, Busuttil RW. Late-Onset Ascites and Nodular Regenerative Hyperplasia After Liver Transplantation. Hepatology 1997;26:347A.
- Fong T-L, Arnaout WS, Hreha GI, Rojter S, Shackleton CR, Petrovic LM, Geller SA, Villamil FG, Colquhoun SD, Vierling JM. Long Term Outcome of Transplantation for Hepatitis C. Hepatology 1999;30:245A.
- Niven PC, Madjor D, Samson A, Lee SR, Green GA, Gwo JR, Fong T-L. Levels of Antibodies to HCV Structural Antigens Correplate with Serum HCV RNA Levels in Chronic Hepatitis C Patients Undergoing Interferon Therapy. Hepatology 1999;30:609A.
- Fong T-L, Govindarajan S, Adkins RH, Post S, Waters RL. Prevalence of HCV Infection in Spinal Cord Injury Patients in the US. 2000 International Symposium on Viral Hepatitis and Liver Disease
- Pruthi JS, Esrason KT, Donovan JA, Medkiff-Munsukhani KA, Paras MV, Fong T-L. Causes of Late Death in Liver Transplant Recipients. Hepatology 2000;32:254A
- Yu AS, Colquhoun SD, Arnaout WS, Pappalardo PA, Sievers T, Geller SA, Sackleton CR, Vierling JM, Fong T-L. Lamivudine Prophylaxis Prevents Replication of HBV in Hepatitis B Core Antibody Positive Livers Following Transplantation. Hepatology 2000;32:293A
- Fong T-L, Pauly M-P, Zacks S, Kahn JA, Sze G, Schulman D, Rodriguez-Torres M, Tsai N, Lyche K, Weston A, Han S. Multi-center randomized trial of 15 mcg Infergen administered daily vs. thrice weekly in patients with chronic hepatitis C who did not respond to interferon therapy. Hepatology 2000;32;349A Hepatology 2000;32
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